BOTOX, short for Botulinum Toxin A, works by binding to nerve endings and preventing the release of chemical transmitters that activate muscles. Botulinum toxin therapy is used to paralyze small muscles of the face which cause frown lines, crow's feet and other wrinkles. It decreases the ability to frown or squint, thereby preventing the appearance of lines and wrinkles caused by repeated facial expressions. BOTOX affects the ability of the muscle to move, but does not impair sensory perception.
How is BOTOX Administered? An extremely diluted amount of Botulinum Toxin A is administered by a physician in the area where a person desires an elimination of wrinkles. Doctors use a fine-gauge needle to inject BOTOX into the skin and muscle. To treat crow's feet, three or more injections are given on the side of the face close to the outer region of the eyes, known as the "orbital rim." Patients should know that injection of BOTOX in the orbital rim, reduces, but does not abolish wrinkles in this area. The result, however, is very satisfying to many people who are self conscious about the appearance of their crow's feet, especially when they smile.
To treat forehead lines, 10 to 16 small dose injections are administered over the forehead area. The goal is to weaken, rather than paralyze the forehead muscle, according to experts. In certain cases, BOTOX can be used to improve the appearance of "laugh lines," the folds in the area between the nose and lips (naso-labial folds). There is a risk, however, of lip drooping or other unfavorable cosmetic results in the mouth area when treating the naso-labial folds. The outer portion of the fold is better treated by other means, such as facelift surgery. Unwanted horizontal lines on the neck, nasal flares and chin creases have also been treated successfully with BOTOX. These areas are treated less frequently.
An alternate method of delivery BOTOX involves the use of a needle, which is connected to an EMG (electromyography) recorder which guides a physician in locating muscles. An audio signal can be heard when the probe comes in contact with the most active part of the muscle. While this technique may allow for more accurate placement of BOTOX, it can be more painful. Experienced physicians in many cases do not require the use of EMG.
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